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Intention-to-Treat Analysis [ITT]

By Jim Frost

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Intention-to-treat (ITT) analysis is a principle used in analyzing randomized controlled trials where all participants are included in the group to which they were originally assigned, regardless of whether they completed the intervention as planned. ITT preserves the benefits of randomization and provides an unbiased estimate of treatment effect.

For example, in a clinical trial testing a new drug, even if some participants stop taking the drug halfway through the study, ITT analysis would still count them in their original treatment group when analyzing the final results.

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